Expert Financial Analysis and Reporting

Overview Kite released a press release with topline data on the interim look at the ZUMA-1 trial. This note interprets information presented in that press release and I would urge you to read it before going on. Key Points: The CR rate at three months for 51 r/r DLBCL patients was 33%. Kite has said […]

Investment Opinion Kite will be reporting interim results of the phase 2, ZUMA-1 trial of its lead product KTE-C19 by the end of September. The most bullish analysts are projecting a very positive outcome in this trial that will result in approval in 2017 and sales of as much as $1 billion of sales by […]

Key Points: I think that an imminent press release dealing with topline results from an interim look at the ZUMA-1 trial will not have much meaningful data even though it is highly anticipated by investors. We will have to wait for the full data set that will be presented at American Society of hematology (ASH) […]

Report Overview This is the third part of the series of reports that I have written on Kite Pharmaceuticals. I have chosen to publish smaller, more digestible parts of an extensive research analysis on Kite instead of one huge report. I hope this will make it easier for subscribers to work their way through what […]

Overview This section tries to give a brief, layman’s overview on the potential role of CAR-T cells in treating certain hematological cancers and the competitive dynamics for companies operating in this space. Kite’s first product is the CAR-T drug KTE-C19. Key Points; There are three CAR-T drugs in development from Kite, Juno and Novartis. They […]

Introduction I have been working on a report on Kite for over three months and have in front of me a rough draft that is about 60 pages long and still evolving. I can’t seem to get the report finished as new areas for investigation just keep coming up. I am also concerned that it […]

Definition of Key Terms Used in This Report Engineered Autologous T-cells (eACTS): These are T-cells that are removed from a patient and genetically engineered to increase their activity against cancer cells. They are then expanded into billions of clones that are reinfused into the patient where they continue to differentiate and attack cancer targets. Chimeric […]

SmithOnStocks Mailbox About the Mailbox: My mailbox comments are brief articles on stocks in which I am involved. These can come from recent events or from subscribers’ questions. They are meant to address specific issues about these stocks and are not full and balanced reports. Please refer to the Reports section of my website for […]

Introduction to This Thought Piece Emerging biotechnology stocks obviously are very hard to value on an absolute basis because they usually have no or minimal sales and huge operating losses. Many Wall Street analysts arrive at price targets by making long term sales and earnings projections; risk adjusting the estimates through predicting probability of successful […]